Bromopride is primarily metabolized by the liver, and its metabolites are excreted via the kidneys. Those who have liver function impairment face a higher threat of drug buildup which may result in elevated toxicity levels. Individuals with significant liver dysfunction should receive adjusted dosages of this drug or avoid it altogether. Clinical studies have shown that Bromopride causes liver damage especially in patients who already suffer from liver disease. The condition known as hepatic encephalopathy develops when the liver fails to detoxify the blood which results in neurological symptoms. Extended use or increased dosage of this medication greatly increases the risk.