While moderate caffeine consumption is generally safe, excessive caffeine intake can lead to increased heart rate and anxiety, which might exacerbate certain side effects of Cenforce 100 mg. To optimize the effectiveness of Cenforce 100 mg, avoid high-fat meals, excessive alcohol, grapefruit and grapefruit juice, excessive caffeine, heavy or spicy foods, and large meals. Adopting these dietary considerations can help enhance the medication's efficacy and minimize potential side effects. Always follow your healthcare provider’s recommendations and consult them if you have any dietary concerns or experience unusual symptoms.