Malegra FXT Plus is marketed as a combination medicine for men experiencing erectile dysfunction (ED) and premature ejaculation (PE). The exact ingredients and strengths can vary by manufacturer and market, so the product packaging should be checked carefully before use. Products sold under the Malegra FXT Plus name commonly combine sildenafil, a PDE5 inhibitor, with an antidepressant-type medicine intended to help delay ejaculation. Sildenafil improves blood flow to the penis during sexual stimulation, helping achieve and maintain an erection.