Silditop 50 mg contains Sildenafil citrate, a medication used to treat erectile dysfunction (ED). It belongs to the class of PDE5 inhibitors, which work by increasing blood flow to the penis to help achieve and maintain an erection during sexual stimulation. During sexual arousal, nitric oxide (NO) is released in the penile tissue, activating cGMP (cyclic guanosine monophosphate). cGMP relaxes smooth muscles in the blood vessels of the penis, allowing increased blood flow and causing an erection. Sildenafil in Silditop 50 mg inhibits PDE5, the enzyme that breaks down cGMP, prolonging the effect and supporting a firm erection.