Cenforce D is usually taken 30–60 minutes before sexual activity. The sildenafil component typically lasts 4–6 hours, supporting erection quality, while dapoxetine helps extend ejaculatory control during this window. It should not be taken more than once in 24 hours, and a doctor may adjust the dose based on age, health status, and treatment response. The medication can be taken with or without food, though fatty meals may delay onset.