Pharma Dry Milling is one of the most important aspects of drug manufacturing in today’s modern world. The purpose of Pharma Dry Milling is to grind solid drug materials in a liquid environment using grinding media. The method provides precise control over particle size and a uniform distribution of material throughout the liquid. Pharma Dry Milling is very beneficial for drugs that are poorly soluble. It improves solubility and increases bioavailability of poorly soluble drugs. In addition, Pharma Dry Milling provides less chance of contamination compared with traditional drying processes, and it allows for more precise temperature control. Because of the high efficiency and reproducibility, many research laboratories and large pharmaceutical production facilities have adopted the Pharma Dry Milling Process into their operations.