Cenforce is a medication that contains Sildenafil Citrate, a PDE‑5 inhibitor used to treat erectile dysfunction (ED). It works by relaxing blood vessels in the penis, increasing blood flow during sexual stimulation.Sildenafil can cause mild decreases in blood pressure because it relaxes blood vessels. For most healthy men, this is usually safe. However, men with pre-existing heart conditions — including severe heart disease, angina, heart failure, arrhythmias, or recent heart attack/stroke — must be cautious.