To protect your eyes from digital eye strain, remember to follow the 20-20-20 rule by taking a 20-second break every 20 minutes to look at something 20 feet away. Adjust your screen settings to optimize brightness, contrast, and consider using a blue light filter. Maintain a proper screen distance and position, keeping it about an arm's length away and slightly below eye level while minimizing glare. Take regular breaks to rest your eyes and stretch your body, and don't forget to blink frequently to keep your eyes moist.