Duratia 60 mg contains dapoxetine, which is a selective serotonin reuptake inhibitor (SSRI) used to treat premature ejaculation (PE) in men. As of my last update, Duratia 60 mg is primarily available as a standalone medication containing dapoxetine. However, it's important to note that dapoxetine is sometimes combined with other medications for the treatment of premature ejaculation. For example, some combination therapies may include both dapoxetine and a phosphodiesterase type 5 (PDE5) inhibitor, such as sildenafil or tadalafil, which are commonly used to treat erectile dysfunction (ED). Duratia 60mg rationale behind combining dapoxetine with a PDE5 inhibitor is to address both the psychological and physiological aspects of sexual dysfunction. Dapoxetine helps delay ejaculation by increasing serotonin levels in the brain, while PDE5 inhibitors improve erectile function by increasing blood flow to the penis. These combination therapies are typically prescribed under the guidance of a healthcare professional, who can determine the most appropriate treatment regimen based on individual factors such as the underlying cause of premature ejaculation, the presence of concurrent erectile dysfunction, and the patient's overall health. If you're considering combination therapy for premature ejaculation, it's important to discuss this with your healthcare provider. They can provide personalized guidance and recommendations based on your specific situation, including potential benefits, risks, and interactions associated with combining medications like Duratia with other drugs.