Common side effects may include headache, flushing, indigestion, back pain, muscle aches, and nasal congestion. Serious side effects such as priapism (prolonged erection lasting more than 4 hours) are rare but require immediate medical attention.As with any medication, it's important to use Tadarise 60 mg as prescribed by a healthcare provider. It should not be taken with nitrates (commonly used for chest pain) or alpha-blockers, as these can interact with tadalafil and cause serious side effects.