In many cases, kidney transplantation is a life-saving surgery for patients with end-stage renal illness. It dramatically raises the quality of life for patients by giving them a fresh start. However, the possibility of organ rejection is one of the main worries after a kidney transplant. In order to ensure that the kidney continues to function properly after the transplant, it is essential to prevent rejection. In addition to providing practical advice for leading a healthy post-transplant lifestyle, this article will examine important preventative measures against kidney transplant rejection.