AnnexMed’s “Commonly Used CPT Codes in Gastroenterology (2025 Guide)” provides a practical, data-driven resource for GI coders, billing specialists, and medical administrators. While gastroenterology doesn’t see as frequent radical code changes as some other specialties, the way existing CPT codes are used, scrutinized, and adjudicated is evolving—and this article walks you through the shifts. It starts by defining what GI procedures encompass: diagnostic and therapeutic scopes (upper GI and colon), biopsies, polyp removal, stents, and the growing use of capsule endoscopy.
Using payer data and usage trends from 2024-2025, AnnexMed identifies which codes are highest in volume—such as 43239 (EGD with biopsy), 45380 (colonoscopy with biopsy), and 45385 (colonoscopy with snare removal)—and points out documentation issues commonly leading to denials. The guide also tracks the rise in capsule endoscopies (codes 91110 & 91113), and covers less common but critical procedures like through-stoma colonoscopies and therapeutic interventions (e.g., mucosal resection, stent placement).
Beyond listing codes, AnnexMed delves into themes that matter: what modifiers are being misused, when prior authorization is becoming more frequently required, how bundling rules are catching practices off guard, and how precise procedure notes (tool used, lesion size or location, use of snare vs forceps, etc.) are decisive in preventing denials. The article also provides a cheat-sheet style reference to high-volume codes, bundling reminders, and payer-specific tips. For any GI practice or coding team, the message is clear: staying current, vigilant, and detail-oriented can help maximise reimbursement and reduce claim issues.