Anti-mycoplasma antibodies are immune proteins that specifically recognize and bind to mycoplasma species, a group of bacteria lacking a cell wall and often associated with respiratory and urogenital infections in humans and animals. These antibodies can be naturally produced by the immune system in response to an infection or can be developed as monoclonal or polyclonal antibodies for diagnostic and research purposes. In laboratory settings, anti-mycoplasma antibodies are crucial for detecting and managing mycoplasma contamination in cell cultures, which can adversely affect cellular function and experimental outcomes. By using these antibodies in assays such as ELISA or immunofluorescence, researchers can quickly identify mycoplasma presence and take corrective actions to ensure the integrity and reliability of biological research involving cell lines.