Shiga toxin 2B (Stx2B) is a subunit of the Shiga toxin family produced by certain strains of Escherichia coli, particularly enterohemorrhagic E. coli (EHEC). It plays a role in toxin assembly and host cell interaction, contributing to pathogenicity. Monoclonal antibodies targeting Stx2B are valuable for neutralization studies, aiding in research and therapeutic applications. Their high specificity enhances detection and treatment strategies in microbiology and infectious disease research.